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[Pro9] Substance P
CAS No. 104486-69-3
[Pro9] Substance P( ——— )
Catalog No. M41618 CAS No. 104486-69-3
[Pro9]-Substance P is a potent, reversible and selective agonist of NK-1 tachykinin receptors with an EC50 of 0.93 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name[Pro9] Substance P
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NoteResearch use only, not for human use.
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Brief Description[Pro9]-Substance P is a potent, reversible and selective agonist of NK-1 tachykinin receptors with an EC50 of 0.93 nM.
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Description[Pro9]-Substance P is a potent, reversible and selective agonist of NK-1 tachykinin receptors with an EC50 of 0.93 nM.
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In Vitro[3H][Pro9]-Substance P can be used as a radio ligand for NK- 1 binding sites.[Pro9]-Substance P stimulates inositol phosphate formation with an efficacy only slightly lower than that of SP (EC50 values of 0.93 ± 0.07 and 0.45 ± 0.06 nM, respectively) on primary cultures of newborn mouse cortical glial cells.
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In Vivo———
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Synonyms———
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PathwayOthers
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TargetOther Targets
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RecptorNK1: 0.93 nM (EC50)]
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Research Area———
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Indication———
Chemical Information
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CAS Number104486-69-3
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Formula Weight1387.73
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Molecular FormulaC66H102N18O13S
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Petitet F, et al. Further demonstration that Pro9-substance P is a potent and selective ligand of NK-1 tachykinin receptors. J Neurochem. 1991 Mar;56(3):879-89.?
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